It can provide theoretical references for further studying on replication, virulence and its determinants, cell and host tropism, pathogenesis, functions of products of genes, attenuation and marker vaccine of CSFV. 为进一步研究猪瘟病毒的复制机理、毒力及其决定因素、致弱机理、致病机理、基因产物的功能、宿主嗜性及标记疫苗的开发提供理论参考。
Common marmosets with negative serum antibodies against hepatitis A virus ( anti HAV) and normal liver functions were used for the tests of passage of H 2 vaccine strain of HAV to explore its residual virulence after attenuation and possibility of its reversion. 为探索甲型肝炎减毒活疫苗的残余毒力及毒力返祖的可能性,将血清抗-HAV阴性,肝功能正常的普通狨猴用于甲型肝炎减毒活疫苗H2株传代试验。
Generation of persistent infection was speculated from virulence attenuation of virulent CSFV under immunity pressures during chronic prevalence. 推测猪瘟病毒持续感染毒株的产生,可能是长期流行的强毒株在免疫压力下毒力弱化的结果。